"The repeated failures of Alzheimer’s drugs in late-stage, hugely expensive trials, have forced Gandy and other researchers to recalibrate any optimism about finding a cure."
"a growing consensus has emerged that, although a drug treatment is desperately needed, people can take concrete steps to reduce their risk of developing Alzheimer’s. “Prevention is the key element if we want to manage this epidemic,” says Miia Kivipelto, a professor, senior geriatrician, and director of Research, Development, Education and Innovation at the Karolinska University Hospital in Stockholm
"One new study published on July 14 in JAMA looked at nearly 200,000 people from the U.K. and showed that an unhealthy lifestyle can increase someone’s chances of developing dementia. A healthy lifestyle, in contrast, can reduce that likelihood, even among those at high genetic risk, the study found."
"Exercise regularly—tons of evidence shows that physical activity can significantly reduce the risk of Alzheimer’s, with a new study finding that exercise slows Alzheimer’s even after amyloid has begun to build up….recommends the U.S. federal guidelines of at least 150 minutes of exercise or other movement a week, including both aerobic activity and muscle training."
"Eat a healthy diet, with lots of vegetables, fruits and healthy oils."
"Sleep—both quality and quantity—is increasingly being shown to be important for Alzheimer’s, she says, though it’s not yet clear whether poor sleep in middle age and beyond is a cause of Alzheimer’s or one of its earliest symptoms."
Researchers are still optimistic about finding disease-altering medicines—just not anytime soon
Posted to FB on 2019-07-23 23:22:06